Currently, the prevalent approach is to contain the spread of the virus by reducing interpersonal contacts and vaccination. An alternative strategy could involve the understanding of the molecular mechanisms underlying the known risk factors and to correct them, when possible, as a prevention/treatment of the disease. The decrease of glutathione (GSH) is one of the biochemical alterations identified as being linked to the risk factors through several clinical research papers globally.
Glutathione has been used clinically through oral, topical, and intravenous route for many years. Several randomized controlled trials and extensive medical literature on glutathione has shown the safety and efficacy of this molecule as an antioxidant, hepatoprotective and anti-inflammatory agent. When the world is struggling to combat a record surge in infections and fatalities with this second wave, Adroit Biomed Limited repurposes the use of glutathione for prevention, management and recovery from Covid 19.
Addressing the Need for role of Glutathione in the age of COVID-19
“Glutathione (GSH), known also as the master anti-oxidant, has been known for its effective immunity generating properties. However, one of its lesser-known properties, as an anti-inflammatory agent has not been in the focus until now. Research published in international journals are evaluating the possible Role of Glutathione in Protecting against the Severe Inflammatory Response Triggered by COVID-19 infection”, shares Dr. Anish Desai Director Strategic Medical Affairs, Adroit Biomed Ltd.
Experts believe somewhere between 10% and 30% of COVID-19 patients develop long-term symptoms, including fatigue, chronic pain, brain fog, shortness of breath and gastrointestinal problems, though the severity of these can vary. Clinical studies reveal that increase in blood Glutathione levels elevate Natural Killer (NK) cell activity upto 400 times and increase Lymphocyte proliferation, Glutathione is also well studied for its anti-inflammatory activity and may prevent cytokine storm. A case report from Russia has documented association of low glutathione levels with higher severity of infections. Additionally, glutathione’s antioxidant, anti-inflammatory and muscle reparative activities helps to recover faster post infection.
The Development Journey:
If you ask anyone on the street what they really hope for in these trying times, they would answer – “a solution”. In this long-winded saga of the century, the bottom line remains protection. With this aim, the pharmaceutical company Adroit Biomed Limited began its focus on formulating “Glutone MD”, #thepocketwarrior which has been designed using a patent-pending Orally Dissolving (OD-Eff) technology formulated with the world’s best and purest Setria Glutathione from Japan. It is the world’s smallest effervescent tablet made to deliver Glutathione through the sublingual / buccal route. When placed sublingually, it quickly makes all of its Glutathione available for absorption. These orange flavoured tablets offer the tasty way to intake the world’s best Glutathione through the most efficient delivery route. Glutone MD is FSSAI compliant.
“There is a rightful paranoia and the need to protect oneself and loved ones from an invisible enemy daily. The formulation Glutone MD has immune enhancing, anti-inflammatory, hepato-protective and muscle reparative, abilities that make it suitable for use in PMR (Prevention, Management & Recovery) of Covid 19. In the organic Vitamin C market, we are amongst the top 5 companies in India”, added Sushant Raorane Director, Adroit Biomed Ltd.
“There is a significant jump in overall demand for nutraceutical products, the second wave of Covid-19 has further reinforced the community disposition towards nutraceuticals. With the likelihood of third wave, industry and community needs to be geared up for war against Covid 19 by revamping our healthcare infrastructure when “Immunity” is the talk of the town. Also, government initiatives like Mission Poshan 2.0 will improve the outreach of immunity enhancers significantly.”, he further adds.